The message (This device is currently in use. Close any programs or windows that might be using the device and then try again) is usually the result of an application, file, open document, music or video file or any other application which is in use (running from the USB flash drive) when you try to remove
it by clicking on the Safely Remove Hardware icon in the notification area.

The error can also be caused if your anti-virus is actively monitoring/scanning the USB drive. Normally, when removing a flash drive from a USB port,
Windows should stop all the read-write operations on the drive so that it can be safely removed. If not, the flash drive can be damaged or data may
be lost or corrupted. However, if Windows determines a file is in use, then it may provide a message which indicates the volume cannot be stopped right now.
So, before ejecting or disconnecting any mass storage device, make sure none of the above activities are performed on the mass storage device before ejecting.

Temporarily disable any security software and then try to remove the hard drive safely.

Antivirus software can help protect your computer against viruses and other security threats. In most cases, you should not disable your
antivirus software. If you do have to temporarily disable it to install other software, you should re-enable it as soon as you’re done. If you are
connected to the Internet or a network during the time your antivirus software is disabled, your computer is vulnerable to attacks.

If that doesn’t help, then go to step 2:

Step 2:

Perform a clean boot to check if a third party program is causing this issue.
1. Click the Start orb on your Desktop
2. Type msconfig in the Start Search box, and then press ENTER.
If you are prompted for an administrator password or for a confirmation, type the password, or click Continue.
3. On the General tab, click Selective Startup.
4. Under Selective Startup, click to clear the Load Startup Items check box.
5. Click the Services tab, click to select the Hide All Microsoft Services check box, and then click Disable All.
6. Click OK.
7. When you are prompted, click Restart.

If this does resolve the issue, then see the following Microsoft Article on “Clean boot” and the section “How to determine what is causing the
problem” to determine which program or service maybe causing the issue.


How to set your computer back, to boot normal:

1. Click the Start on your Desktop
2. In the Start Search box, type msconfig, and then press ENTER.
If you are prompted for an administrator password or for a confirmation, type the password, or click Continue.
3. Click the General tab.
4. Click Normal Startup – load all device drivers and services, and then click OK.
5. When you are prompted, click Restart to restart the computer.

You may also follow the suggestions given by user “Divya” in the thread link mentioned below:

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